woman in blue scrubs sitting on a table using a stethoscope to listen to a grey and white cat sitting on the table looking a t the camera

All Active Feline Clinical Trials

New studies are being added all the time – check back soon if you don’t see one available for your cat!


Image of brown, black, and white cat laying in a basket

Evaluating Potential Blood Biomarkers for Feline Heart Disease (HCM)

Complete Title: Evaluation of Potential Novel Biomarkers for Feline Hypertrophic Cardiomyopathy

Study Investigator: Dr. Sonja Fonfara

Researchers at OVC have identified a set of genes that are differently expressed in hearts from cats with Hypertrophic Cardiomyopathy (HCM) compared to healthy cats. The products of these genes are known to be released into the blood and might therefore be useful as markers for HCM.

Inclusion criteria (two groups):

  • Healthy, male cats ≥ 2 years – RECRUITMENT COMPLETE FOR THIS GROUP
  • Female and male cats ≥ 2 years with HCM and no concurrent medical conditions

Image of white, brown, and black cat sitting

Comparison of Small Molecules in the Blood Samples of Cats With and Without Heart Disease

Complete Title: Circulating miRNA profiles in cats with and without hypertrophic cardiomyopathy


Diagnostic Imaging

Emergency and Critical Care

Internal Medicine

Image of two black, grey and white kittens laying in a fuzzy basket

Assessment of a Novel Urine Biomarker for Acute Kidney Injury in Cats

Complete Title: Feline Acute Kidney Injury Study

Study Investigator: Dr. Dorothee Bienzle

Acute kidney injury (AKI) occurs when there is a sudden failure of the kidneys to perform their normal filtration duties. If diagnosed early and treated aggressively, AKI is potentially reversible. Not all cats with AKI have the
same laboratory blood results (ie: serum creatinine concentration may not be elevated) which can make diagnosis problematic, however, there may be a new
biomarker in urine that we can use to diagnose AKI.

Inclusion criteria:

  • Severe systemic disease (including cancer)
  • Aminoglycoside & NSAID therapies
  • Low urinary tract obstruction
  • Prerenal azotemia
  • Exacerbation of chronic renal disease
  • Acute renal failure



Image of white and grey domestic short hair cat lying on pug

Companion Animal (Cats and Dogs) Tumour Sample Bank

Complete Title: Companion Animal Tumour Sample Bank

Study Investigator:

The objective of this bank is to allow for translation of cancer research throughout the University of Guelph and greater community to improve lives of those with companion animals that have cancer.

Inclusion criteria:

  • Companion animals with a confirmed diagnosis of cancer and the presence of a tumour



Questions about these studies?