a white jack Russell terrier with black and brown spots laying on a desk as a woman wearing purple gloves and a stethoscope holds the dog in place while writing on a clipboard.

Canine Internal Medicine Clinical Studies

The Companion Animal Internal Medicine service at the Ontario Veterinary College (OVC) provides comprehensive clinical trials to further veterinary research in the diagnosis and treatment of numerous diseases. The Companion Animal Internal Medicine service is specialized in offering diagnostic tests and procedures for immunologic, endocrine, infectious, genetic and toxic diseases; diseases of the liver, pancreas and gastrointestinal tract; diseases of the kidney and urinary tract, and disease of the respiratory system. To learn more about the Companion Animal Internal Medicine service at the OVC, please click here.


Small while and black dog (Yorkie) looks up at the camera.

How Well Do Dissolvable Capsule Cameras Work in Small Dogs for Gut Imaging?

Study Investigator: Dr. Alice Defarges

Capsule endoscopy has revolutionized the approach of endoscopy in humans and dogs, allowing for the evaluation of the entire gut in a minimally invasive way, without the need for general anesthesia. Dissolvable non-endoscopic capsules are commonly used in medium to large breed dogs for gut imaging. The utility and speed at which the capsule passes through the gut of small breed dogs has not been evaluated.

Financial incentives are available. This study is partially funded by OVC Pet Trust.

Inclusion criteria:

  • Healthy dogs between 3 and 8 kg, receiving no medication affecting gut motility (i.e. prokinetics or opioids), no vomiting, diarrhea or regurgitations in the last month

Image of brown and black pug walking with tongue out.

ON HOLD FOR RECRUITMENT – Evaluating the Impact of Elective Surgery on the Gut Bacteria of Dogs

Scientific Title: Impact of Elective Orthopedic Surgery on the Fecal Microbiome of Dogs

Study Investigator: Dr. Shauna Blois

The gut microbiome is a collection of bacteria and other microorganisms living within the gastrointestinal tract, including many beneficial bacteria. When dogs have surgery, this may change the microbiome population and these changes could have an impact on a dog’s overall health.

Inclusion criteria:

  • Dogs undergoing elective orthopedic surgery (e.g., TPLO, etc) at OVC, with no newly diagnosed conditions within 1 month of surgery

Questions about these studies?