Canine Internal Medicine Clinical Studies

The Companion Animal Internal Medicine service at the Ontario Veterinary College (OVC) provides comprehensive clinical trials to further veterinary research in the diagnosis and treatment of numerous diseases. The Companion Animal Internal Medicine service is specialized in offering diagnostic tests and procedures for immunologic, endocrine, infectious, genetic and toxic diseases; diseases of the liver, pancreas and gastrointestinal tract; diseases of the kidney and urinary tract, and disease of the respiratory system. To learn more about the Companion Animal Internal Medicine service at the OVC, please click here.


NEW STUDY – Evaluating the Impact of Elective Surgery on the Gut Bacteria of Dogs

Complete Title: Impact of Elective Orthopedic Surgery on the Fecal Microbiome of Dogs

The purpose of this research is to determine the effects of elective orthopedic surgery on the gut microbiome. The gut microbiome is a collection of bacteria and other microorganisms living within the gastrointestinal tract, including many beneficial bacteria. Surgery could impact the microbiome population, and changes in the microbiome could be linked to health status.

Inclusion criteria:

  • Dogs undergoing any elective orthopedic surgery (e.g., TPLO), with no other diagnosed illnesses in 1 month prior to surgery

Measuring How Drugs Affect the Speed of Transit Through the Gastrointestinal Tract via a Swallowed Video Recording Device

Complete Title: Effect of Metoclopramide and Erythromycin on Gastrointestinal Transit Time in Healthy Dogs Measured by Video Endoscopy

The objective of this study is to determine if the use of prokinetic drugs prior to capsule administration results in a higher rate of complete studies.

Inclusion Criteria:

  • (Dogs owned by internal (OVC) or external veterinary professionals)
  • Healthy dogs ≥10 kg not on any medication affecting gut motility (i.e. prokinetics, levothyroxine or opioids) with no adverse GI signs within the last 2 months (vomiting, diarrhea, or regurgitation) and no chronic gastroenteropathy

Questions about these studies?